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Reposted

Moderna's mRNA platform uses N1-methylpseudouridine to evade immune detection. A single chemical modification that made mRNA drugs possible.

CAS
CAS@cas·Jul 25

CPHI Italy !!

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Boehringer's tiotropium bromide (Spiriva) required a novel crystallization route to isolate the pure enantiomer. Chiral chemistry breathing easier for millions.

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Moderna's mRNA platform uses N1-methylpseudouridine to evade immune detection. A single chemical modification that made mRNA drugs possible.

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Siegfried's novel synthetic route reduced 12 steps to 7 — saving 40 tons of waste per ton of API. Process chemistry optimization is green chemistry.

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Recipharm's sterile manufacturing fills injectable drugs in isolator technology. Advanced synthesis handles highly potent APIs with containment at nanogram limits.

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Catalent's softgel technology — gelatin capsules encasing liquid drug formulations — improves bioavailability of poorly soluble drugs. Lipid and nanoparticle platforms.

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Schrödinger's FEP+ predicts protein-ligand binding affinities within 1 kcal/mol — quantum chemistry guiding drug design. Physics-based simulation replacing trial-and-error.

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IMCD@imcdnv·Jul 19

IMCD's technical centers formulate personal care creams, coating systems, and pharma tablets. 3,600+ employees translating raw chemicals into finished products.

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Imerys' talc from Luzenac (France) — the world's purest deposit — improves plastic stiffness and paint matting. Bentonite clarifies wine and foundry sand.

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Perstorp's pentaerythritol — condensing formaldehyde and acetaldehyde — crosslinks alkyd resins in coatings. Capa caprolactone polyols serve biodegradable PU and 3D printing resins.

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OCP controls 70% of global phosphate reserves — Morocco's Khouribga and Benguérir mines hold ancient marine sediment bounty. Phosphorus for fertilizer, food, and DNA.

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ALTANA's ECKART effect pigments — aluminum flakes coated with iron oxide — create color-shift paint on luxury cars. BYK additives control coating rheology.

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Tata Chemicals mines trona at Magadi, Kenya — a Rift Valley soda lake deposit. Solvay process turns trona into pure Na2CO3 for glass, chemicals, and detergents.

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Tongkun produces 10Mt/year polyester filament — the yarn in clothing, carpets, and upholstery. PTA+MEG→PET melt-spinning at world-leading scale.

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Hengyi's Brunei PMB refinery-cracker integrates crude to aromatics to polyester feedstock. Southeast Asia's largest integrated petchem complex.

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Rongsheng's Zhoushan refinery processes 40Mt crude annually, feeding paraxylene for PTA, then polyester fibers. Full-chain integration: one barrel of crude becomes the shirt on your back.

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Coromandel's multi-step synthesis — from simple aromatics to complex heterocyclic crop protection actives — demonstrates India's growing role in global fine chemistry supply chains. Purity and precision at competitive cost.

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Jacobi's coconut-shell activated carbon — steam-activated at 900°C to create 1200 m²/g surface area — adsorbs PFAS, chlorine, and volatile organics from drinking water. A single gram holds the surface of a football field.

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