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  • Posted @SELL
  • CB-1158-analog,1345810-21-0,DC Chemicals Limited

供应信息 2021-1-6 21:44 165
IP: Reserved

CB-1158-analog

更新时间:2020-12-18 22:54:27 采购访问:1次

常用名 CB-1158-analog CAS号 1345810-21-0
价格 $需询单/100mg $需询单/250mg $需询单/500mg 纯度 98.0%
备货期 3天 库存 现货
产品网页 http://www.dcchemicals.com/product_show-CB-1158-analog.html
 产品详情(用途,包装等)
CB-1158-analog, also known as Numidargistat-analog and INCB01158-analog, is a potent and orally active arginase inhibitor with IC50=89 nM) . CB-1158 blocked myeloid cell-mediated suppression of T cell proliferation in vitro and reduced tumor growth in multiple mouse models of cancer, as a single agent and in combination with checkpoint blockade, adoptive T cell therapy, adoptive NK cell therapy, and the chemotherapy agent gemcitabine. CB-1158 increased tumor-infiltrating CD8+ T cells and NK cells, inflammatory cytokines, and expression of interferon-inducible genes. CB-1158 may be potentially useful in renal cell cancer, breast cancer, non-small cell lung cancer, acute myeloid leukemia, and other tumor types where arginase-secreting MDSCs are known to play an immunosuppressive role. (see ADDITIONAL INFORMATION in this web page for CB-1158 structure confusion).

供应商信息

DC Chemicals Limited

认证状态:已认证供应商
商品数:20124件
电话:58447131
地址:浦东新区金豫路100号
地区: 上海市 上海市 浦东新区
联系人:Tony Cao
联系人电话:862158447131
邮件:sales@dcchemicals.com
网址:http://www.dcchemicals.com
年贸易额:>1000万
D&C Chemicals provides a wide range of research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and Natural compounds for laboratory and scientific use.



D&C Chem has established a global network of thousands of customers from many research centers and Reagent companies in the USA, Europe and Japan.

We are the the official vendor of more than 500 universities and institutes including: Harvard University,Yale University,NIH/NCI, City of Hope ORG, PARTNERS ORG,John Hopkins University,Universit tsklinikum,Oxford University,Newcastle University,UNC,UCSF and many other universities and institutes. Our bioactive compounds received good feedback from our customers.





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