Sitravatinib malate
更新时间:2020-12-18 22:54:27
采购访问:1次
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常用名 |
Sitravatinib malate |
CAS号 |
2244864-88-6 |
价格 |
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纯度 |
98.0% |
备货期 |
3天 |
库存 |
现货 |
产品网页 |
http://www.dcchemicals.com/product_show-Sitravatinib-malate.html |
产品详情(用途,包装等) Sitravatinib malate (MGCD516 malate) is an orally bioavailable receptor tyrosine kinase (RTK) inhibitor with IC50s of 1.5 nM, 2 nM, 2 nM, 5 nM, 6 nM, 6 nM, 8 nM, 0.5 nM, 29 nM, 5 nM, and 9 nM for Axl, MER, VEGFR3, VEGFR2, VEGFR1, KIT, FLT3, DDR2, DDR1, TRKA, TRKB, respectively. Sitravatinib malate shows potent single-agent antitumor efficacy and enhances the activity of PD-1 blockade through promoting an antitumor immune microenvironment. |
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