Syk Inhibitor
更新时间:2020-12-18 22:54:27
采购访问:1次
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常用名 |
3-(1-甲基吲哚-3-亚甲基)-2-氧代-2,3-二氢吲哚-5-磺酸酰胺 |
CAS号 |
622387-85-3 |
价格 |
$需询单/100mg $需询单/250mg $需询单/500mg |
纯度 |
98.0% |
备货期 |
3天 |
库存 |
现货 |
产品网页 |
http://www.dcchemicals.com/product_show-Syk_Inhibitor.html |
产品详情(用途,包装等) OXSI-2 is an Syk Inhibitor. OXSI-2 blocks nigericin-induced inflammasome signaling and pyroptosis independent of potassium efflux. OXSI-2 inhibits inflammasome assembly, caspase-1 activation, IL-1β processing and release, mitochondrial ROS generation, and pyroptotic cell death. Using a novel live cell potassium sensor we show that Syk inhibition with OXSI-2 has no effect on potassium efflux kinetics and that blockade of potassium efflux with extracellular potassium alters Syk phosphorylation. |
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