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CAS号:
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945553-91-3
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英文名称:
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R-afatinib
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英文同义词:
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AFATINIB-2;Afatinib-2;Afatinib Enantiomer;(E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3R)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide;2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3R)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-;(R,E)-N-(4-((3-Chloro-4- fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinozolin- 6-yl)-4-(dimethylamino)but-2-enamide;(R,E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetra- hydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino) but-2-enamide;2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3R)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-, (2E)-;Afatinib impurity 3/R-afatinib/(2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3R)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide
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中文名称:
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R-阿法替尼
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中文同义词:
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阿法替尼对映异构体杂质;阿法替尼手性异构体杂质;阿法替尼杂质A(异构体);(R,E)-N-{4-[(3-氯-4-氟苯基)氨基]-7-[(四氢呋喃-3-基)氧基]喹唑啉-6-基}-4-(二甲基氨基)丁-2-烯酰胺
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分子式:
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C24H25ClFN5O3
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分子量:
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485.94
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- 沸点 :
- 676.9±55.0 °C(Predicted)
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- 密度 :
- 1.380±0.06 g/cm3(Predicted)
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- 酸度系数(pKa):
- 11.79±0.43(Predicted)
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